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Ataxin 1 antibody (C-Term)

This anti-Ataxin 1 antibody is a Mouse Monoclonal antibody detecting Ataxin 1 in WB, IHC and FACS. Suitable for Human, Mouse and Rat.
Catalog No. ABIN7602773

Quick Overview for Ataxin 1 antibody (C-Term) (ABIN7602773)

Target

See all Ataxin 1 (ATXN1) Antibodies
Ataxin 1 (ATXN1)

Reactivity

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  • 63
  • 34
  • 2
  • 1
  • 1
  • 1
  • 1
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  • 1
Human, Mouse, Rat

Host

  • 67
  • 51
  • 1
Mouse

Clonality

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Monoclonal

Conjugate

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  • 7
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  • 4
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Ataxin 1 antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone

2B13G8
  • Binding Specificity

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    • 7
    • 3
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    • 2
    • 2
    • 2
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    • 1
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    C-Term

    Purpose

    Anti-Ataxin 1 Antibody Picoband® (monoclonal, 2B13G8)

    Cross-Reactivity (Details)

    No cross-reactivity with other proteins.

    Characteristics

    Anti-Ataxin 1 Antibody Picoband® (monoclonal, 2B13G8) (ABIN7602773). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the C-terminus of human Ataxin 1, different from the related mouse and rat sequences by one amino acid.

    Isotype

    IgG2b
  • Application Notes

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse, Rat
    1. "Entrez Gene: ATXN1 ataxin 1" 2. Tong, X., Gui, H., Jin, F., Heck, B. W., Lin, P., Ma, J., Fondell, J. D., Tsai, C.-C. Ataxin-1 and brother of ataxin-1 are components of the Notch signalling pathway. EMBO Rep. 12: 428-435, 2011. 3. Volz A, Fonatsch C, Ziegler A (Jun 1992). "Regional mapping of the gene for autosomal dominant spinocerebellar ataxia (SCA1) by localizing the closely linked D6S89 locus to 6p24.2----p23.05". Cytogenet Cell Genet 60 (1): 37-9. 4. Volz, A., Boyle, J. M., Cann, H. M., Cottingham, R. W., Orr, H. T., Ziegler, A. Report of the second international workshop on human chromosome 6. Genomics 21: 464, 1994.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Storage

    4 °C,-20 °C

    Storage Comment

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    Ataxin 1 (ATXN1)

    Alternative Name

    ATXN1

    Background

    Synonyms: CD2-associated protein, Adapter protein CMS, Cas ligand with multiple SH3 domains, CD2AP

    Tissue Specificity: Widely expressed in fetal and adult tissues.

    Background: Ataxin-1 is a protein that in humans is encoded by the ATXN1 gene. The ATXN1 gene had been mapped to 6p23 by in situ hybridization. Ataxin-1 (ATXN1), a causative factor for spinocerebellar ataxia type 1 (SCA1), and the related Brother of ATXN1 (BOAT1) are human proteins involved in transcriptional repression. ATXN1 and BOAT1 might participate in several Notch-controlled developmental and pathological processes.

    Molecular Weight

    105 kDa

    Gene ID

    6310

    UniProt

    P54253

    Pathways

    Synaptic Membrane
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