RAB1B antibody (C-Term)
Quick Overview for RAB1B antibody (C-Term) (ABIN7602809)
Target
See all RAB1B AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Purpose
- Anti-RAB1B Antibody Picoband®
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Characteristics
- Anti-RAB1B Antibody Picoband® (ABIN7602809). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Purification
- Immunogen affinity purified.
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Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human RAB1B, which shares 100% and 96.8% amino acid (aa) sequence identity with mouse and rat RAB1B, respectively.
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Isotype
- IgG
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Application Notes
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse
1. Alvarez, C., Garcia-Mata, R., Brandon, E., Sztul, E. COPI recruitment is modulated by a Rab1b-dependent mechanism. Molec. Biol. Cell 14: 2116-2127, 2003. 2. Chen, D., Guo, J., Gahl, W. A. RAB GTPases expressed in human melanoma cells. Biochim. Biophys. Acta 1355: 1-6, 1997. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 1/29/2009. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.005 mg Sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RAB1B (RAB1B, Member RAS Oncogene Family (RAB1B))
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Alternative Name
- RAB1B
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Background
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Synonyms: Thioredoxin, mitochondrial, MTRX, Mt-Trx, Thioredoxin-2, TXN2, TRX2
Tissue Specificity: Widely expressed in adult (at protein level) and fetal tissues.
Background: Ras-related protein Rab-1B is a protein that in humans is encoded by the RAB1B gene. Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi.
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Molecular Weight
- 24 kDa
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Gene ID
- 81876
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UniProt
- Q9H0U4
Target
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