CNN2 antibody (C-Term)

Catalog No. ABIN7602856

The Rabbit Polyclonal anti-CNN2 antibody has been validated for WB, IHC and FACS. It is suitable to detect CNN2 in samples from Human.

Quick Overview for CNN2 antibody (C-Term) (ABIN7602856)

Target: CNN2 (Calponin 2 (CNN2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-CNN2 Antibody

Binding Specificity: C-Term

Purpose: Anti-Calponin 2/CNN2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Calponin 2/CNN2 Antibody Picoband® (ABIN7602856). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Calponin 2/CNN2, which shares 75% amino acid (aa) sequence identity with mouse CNN2.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Cheng, J.-F., Boyartchuk, V., Zhu, Y. Isolation and mapping of human chromosome 21 cDNA: progress in constructing a chromosome 21 expression map. Genomics 23: 75-84, 1994. 2. Gross, M. B. Personal Communication. Baltimore, Md. 2/16/2011. 3. Masuda, H., Tanaka, K., Takagi, M., Ohgami, K., Sakamaki, T., Shibata, N., Takahashi, K. Molecular cloning and characterization of human non-smooth muscle calponin. J. Biochem. 120: 415-424, 1996.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for CNN2

Target: CNN2 (Calponin 2 (CNN2))

Alternative Name: CNN2

Background:

Synonyms: Annexin A8 ,Annexin VIII ,Annexin-8 ,Vascular anticoagulant-beta ,VAC-beta ,ANXA8 ,ANX8,

Tissue Specificity: Ubiquitously expressed.

Background: Calponin 2 is a protein that in humans is encoded by the CNN2 gene. The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several pseudogenes of this gene have been identified, and are present on chromosomes 1, 2, 3, 6, 9, 11, 13, 15, 16, 21 and 22. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 34 kDa

Gene ID: 1265

UniProt: Q99439