Elastase 4 antibody (C-Term)

Catalog No. ABIN7602872

Product Details anti-Elastase 4 Antibody

Target: Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))

Binding Specificity: C-Term

Reactivity: Rat, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Elastase 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: Anti-CTRC Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-CTRC Antibody Picoband® (ABIN7602872). Tested in WB, IHC applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CTRC, which shares 86.4% amino acid (aa) sequence identity with both mouse and rat CTRC.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunohistochemistry, 2-5 μg/mL, Rat
1. Kang, J., Wiegand, U., Muller-Hill, B. Identification of cDNAs encoding two novel rat pancreatic serine proteases. Gene 110: 181-187, 1992. 2. Masson, E., Chen, J.-M., Scotet, V., Le Marechal, C., Ferec, C. Association of rare chymotrypsinogen C (CTRC) gene variations in patients with idiopathic chronic pancreatitis. Hum. Genet. 123: 83-91, 2008. 3. Rosendahl, J., Witt, H., Szmola, R., Bhatia, E., Ozsvari, B., Landt, O., Schulz, H.-U., Gress, T. M., Ptufzer, R., Lohr, M., Kovacs, P., Bluher, M., and 22 others. Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis. Nature Genet. 40: 78-82, 2008.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for Elastase 4

Target: Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))

Alternative Name: CTRC (CTRC Products)

Background:

Synonyms: CTRC, CLCR, Chymotrypsin-C, EC 3.4.21.2, Caldecrin

Background: This gene encodes a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

Molecular Weight: 34 kDa

Gene ID: 11330

UniProt: Q99895