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EPH Receptor A4 antibody (C-Term)

This Rabbit Polyclonal antibody specifically detects EPH Receptor A4 in WB. It exhibits reactivity toward Human.
Catalog No. ABIN7602882

Quick Overview for EPH Receptor A4 antibody (C-Term) (ABIN7602882)

Target

See all EPH Receptor A4 (EPHA4) Antibodies
EPH Receptor A4 (EPHA4)

Reactivity

  • 78
  • 35
  • 21
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 92
  • 7
  • 1
  • 1
Rabbit

Clonality

  • 89
  • 8
  • 2
Polyclonal

Conjugate

  • 49
  • 9
  • 8
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This EPH Receptor A4 antibody is un-conjugated

Application

  • 57
  • 48
  • 35
  • 14
  • 13
  • 13
  • 13
  • 11
  • 8
  • 5
  • 4
  • 2
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 15
    • 11
    • 9
    • 9
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Purpose

    Anti-EPHA4 Antibody Picoband®

    Cross-Reactivity (Details)

    No cross-reactivity with other proteins

    Characteristics

    Anti-EPHA4 Antibody Picoband® (ABIN7602882). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the C-terminus of human EPHA4. Human EPHA4 shares 100% amino acid (aa) sequence identity with mouse EPHA4.

    Isotype

    IgG
  • Application Notes

    Western blot, 0.25-0.5 μg/mL, Human
    1. Cowan, C. A., Yokoyama, N., Bianchi, L. M., Henkemeyer, M., Fritzsch, B. EphB2 guides axons at the midline and is necessary for normal vestibular function. Neuron 26: 417-430, 2000. 2. Dottori, M., Hartley, L., Galea, M., Paxinos, G., Polizzotto, M., Kilpatrick, T., Bartlett, P. F., Murphy, M., Kontgen, F., Boyd, A. W. EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract. Proc. Nat. Acad. Sci. 95: 13248-13253, 1998. 3. Fox, G. M., Holst, P. L., Chute, H. T., Lindberg, R. A., Janssen, A. M., Basu, R., Welcher, A. A. cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases. Oncogene 10: 897-905, 1995.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Storage

    4 °C,-20 °C

    Storage Comment

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    EPH Receptor A4 (EPHA4)

    Alternative Name

    EPHA4

    Background

    Synonyms: EPHA4, HEK8, SEK, TYRO1, Ephrin type-A receptor 4, EC 2.7.10.1, EPH-like kinase 8, EK8, hEK8, Tyrosine-protein kinase TYRO1, Tyrosine-protein kinase receptor SEK

    Background: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Multiple transcript variants encoding different isoforms have been found for this gene.

    Molecular Weight

    110 kDa

    Gene ID

    2043

    UniProt

    P54764

    Pathways

    RTK Signaling
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