GPR35 antibody (C-Term)

Catalog No. ABIN7602891

This Rabbit Polyclonal antibody specifically detects GPR35 in WB and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for GPR35 antibody (C-Term) (ABIN7602891)

Target: GPR35 (G Protein-Coupled Receptor 35 (GPR35))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR35 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-GPR35 Antibody

Binding Specificity: C-Term

Purpose: Anti-GPR35 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-GPR35 Antibody Picoband® (ABIN7602891). Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human GPR35. Human GPR35 shares 95% amino acid (aa) sequence identity with mouse GPR35.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Horikawa, Y., Oda, N., Cox, N. J., Li, X., Orho-Melander, M., Hara, M., Hinokio, Y., Lindner, T. H., Mashima, H., Schwarz, P. E. H., del Bosque-Plata, L., Horikawa, Y., and 14 others. Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nature Genet. 26: 163-175, 2000. Note: Erratum: Nature Genet. 26: 502 only, 2000. 2. Maravillas-Montero, J. L., Burkhardt, A. M., Hevezi, P. A., Carnevale, C. D., Smit, M. J., Zlotnik, A. Cutting edge: GPR35/CXCR8 is the receptor of the mucosal chemokine CXCL17. J. Immun. 194: 29-33, 2015. 3. O'Dowd, B. F., Nguyen, T., Marchese, A., Cheng, R., Lynch, K. R., Heng, H. H. Q., Kolakowski, L. F., Jr., George, S. R. Discovery of three novel G-protein-coupled receptor genes. Genomics 47: 310-313, 1998.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for GPR35

Target: GPR35 (G Protein-Coupled Receptor 35 (GPR35))

Alternative Name: GPR35

Background:

Synonyms: GPR35, G-protein coupled receptor 35, Kynurenic acid receptor, KYNA receptor

Background: Enables C-X-C chemokine receptor activity. Involved in chemokine-mediated signaling pathway, negative regulation of voltage-gated calcium channel activity, and positive regulation of cytosolic calcium ion concentration. Located in plasma membrane.

Molecular Weight: 34 kDa

Gene ID: 2859