TMEM88 antibody (C-Term)

Catalog No. ABIN7602936

Product Details anti-TMEM88 Antibody

Target: TMEM88 (Transmembrane Protein 88 (TMEM88))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM88 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Purpose: Anti-TMEM88 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TMEM88 Antibody Picoband® (ABIN7602936). Tested in ICC/IF, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TMEM88, which shares 86.7% amino acid (aa) sequence identity with mouse TMEM88.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
1. Lee, H.-J., Finkelstein, D., Li, X., Wu, D., Shi, D.-L., Zheng, J. J. Identification of transmembrane protein 88 (TMEM88) as a Dishevelled-binding protein. J. Biol. Chem. 285: 41549-41556, 2010. 2. Palpant, N. J., Pabon, L., Rabinowitz, J. S., Hadland, B. K., Stoick-Cooper, C. L., Paige, S. L., Bernstein, I. D., Moon, R. T., Murry, C. E. Transmembrane protein 88: a Wnt regulatory protein that specifies cardiomyocyte development. Development 140: 3799-3808, 2013.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for TMEM88

Target: TMEM88 (Transmembrane Protein 88 (TMEM88))

Alternative Name: TMEM88 (TMEM88 Products)

Background:

Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8, CPAMD8, KIAA1283

Tissue Specificity: Highly expressed in the kidney, brain and testis and to a lower extent in heart, liver and small intestine. Expressed in the lens, cornea and retina. Strongly expressed in the distal tips of the retinal neuroepithelium that form the iris and ciliary body.

Background: Predicted to enable PDZ domain binding activity. Involved in negative regulation of canonical Wnt signaling pathway, protein localization to plasma membrane, and protein stabilization. Located in cytosol and plasma membrane.

Molecular Weight: 22 kDa

Gene ID: 92162