TRADD antibody (Cytoplasmic Domain, Cytosolic)

Catalog No. ABIN7602957

This Rabbit Monoclonal antibody specifically detects TRADD in WB, IHC, IF, IP and ICC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TRADD antibody (Cytoplasmic Domain, Cytosolic) (ABIN7602957)

Target: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TRADD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: ADCA-20

Product Details anti-TRADD Antibody

Binding Specificity: Cytoplasmic Domain, Cytosolic

Purpose: Anti-TRADD Monoclonal Antibody

Characteristics: Anti-TRADD Monoclonal Antibody (ABIN7602957). Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human TRADD Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:10

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for TRADD

Target: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Alternative Name: TRADD

Background:

Synonyms: Cytoplasmic aconitate hydratase,Aconitase,4.2.1.3,Citrate hydro-lyase,Ferritin repressor protein,Iron regulatory protein 1,IRP1,Iron-responsive element-binding protein 1,IRE-BP 1,ACO1,IREB1,

Tissue Specificity: Widely expressed.

Molecular Weight: 70 kDa, 90 kDa

UniProt: Q15628

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C