CXCR3 antibody (Isoform 2)

Catalog No. ABIN7602960

This Rabbit Monoclonal antibody specifically detects CXCR3 in WB, ICC, IF and IP. It exhibits reactivity toward Human.

Quick Overview for CXCR3 antibody (Isoform 2) (ABIN7602960)

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CXCR3 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: ACFD-3

Product Details anti-CXCR3 Antibody

Binding Specificity: Isoform 2

Purpose: Anti-CXCR3 Monoclonal Antibody

Characteristics: Anti-CXCR3 Monoclonal Antibody (ABIN7602960). Tested in WB, ICC/IF, IP applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human CXCR3 Receptor for CXCL9, CXCL10 and CXCL11 and mediates the proliferation of human mesangial cells (HMC) . Isoform 2 is a receptor for CXCL4 and also mediates the inhibitory activities of CXCL9, CXCL10 and CXCL11 on the growth of human microvascular endothelial cells (HMVEC) . May play a role in angiogenesis.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
ICC/IF 1:50-1:200
IP 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for CXCR3

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Alternative Name: CXCR3

Background:

Synonyms: Proto-oncogene tyrosine-protein kinase receptor Ret,2.7.10.1,Cadherin family member 12,Proto-oncogene c-Ret,Soluble RET kinase fragment,Extracellular cell-membrane anchored RET cadherin 120 kDa fragment,RET,CDHF12, CDHR16, PTC, RET51,

Tissue Specificity: Widely expressed, with extremely low levels in brain. .

Molecular Weight: 3 kDa

UniProt: P49682