SET/TAF-I antibody (Isoform 2)

Catalog No. ABIN7602961

The Rabbit Monoclonal anti-SET/TAF-I antibody has been validated for WB, IHC, IF, IP, FACS and ICC. It is suitable to detect SET/TAF-I in samples from Human, Mouse and Rat.

Quick Overview for SET/TAF-I antibody (Isoform 2) (ABIN7602961)

Target: SET/TAF-I (SET) (SET Nuclear Oncogene (SET))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SET/TAF-I antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: AEEO-19

Product Details anti-SET/TAF-I Antibody

Binding Specificity: Isoform 2

Purpose: Anti-SET Monoclonal Antibody

Characteristics: Anti-SET Monoclonal Antibody (ABIN7602961). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human SET Multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone binding. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000
IHC 1:50-1:200
ICC/IF 1:100-1:500
IP 1:30
FC 1:20

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for SET/TAF-I

Target: SET/TAF-I (SET) (SET Nuclear Oncogene (SET))

Alternative Name: SET

Background:

Synonyms: Caspase-10,CASP-10,3.4.22.63,Apoptotic protease Mch-4,FAS-associated death domain protein interleukin-1B-converting enzyme 2,FLICE2,ICE-like apoptotic protease 4,Caspase-10 subunit p23/17,Caspase-10 subunit p12,CASP10,MCH4,

Tissue Specificity: Detectable in most tissues. Lowest expression is seen in brain, kidney, prostate, testis and colon.

Molecular Weight: 80 kDa

UniProt: Q01105

Pathways: Apoptosis