SCRN2 antibody (Middle Region)

Catalog No. ABIN7603087

Product Details anti-SCRN2 Antibody

Target: SCRN2 (Secernin 2 (SCRN2))

Binding Specificity: Middle Region

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCRN2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Anti-SCRN2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SCRN2 Antibody Picoband® (ABIN7603087). Tested in WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human SCRN2, identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Rat
1. Way, G., Morrice, N., Smythe, C., O'Sullivan, A. J. Purification and identification of secernin, a novel cytosolic protein that regulates exocytosis in mast cells. Molec. Biol. Cell 13: 3344-3354, 2002.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SCRN2

Target: SCRN2 (Secernin 2 (SCRN2))

Alternative Name: SCRN2 (SCRN2 Products)

Background:

Synonyms: Kelch repeat and BTB domain-containing protein 2, BTB and kelch domain-containing protein 1, KBTBD2, BKLHD1, KIAA1489

Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Background: SCRN2 is a member of the secernin family of proteins which includes the homologous SCRN1, a protein that was first identified as being involved in the regulation of exocytosis from peritoneal mast cells. Little is known of SCRN2, but studies have shown that SCRN1 may possess epitopes that function as tumor-associated antigens in gastric cancers and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN2 may also be involved in protein secretion or the regulation of cell growth.

Molecular Weight: 42 kDa

Gene ID: 90507