SEPHS1 antibody (Middle Region)

Catalog No. ABIN7603088

This anti-SEPHS1 antibody is a Rabbit Polyclonal antibody detecting SEPHS1 in WB and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for SEPHS1 antibody (Middle Region) (ABIN7603088)

Target: SEPHS1 (Selenophosphate Synthetase 1 (SEPHS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEPHS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SEPHS1 Antibody

Binding Specificity: Middle Region

Purpose: Anti-Selenophosphate synthetase 1/SEPHS1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Selenophosphate synthetase 1/SEPHS1 Antibody Picoband® (ABIN7603088). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Selenophosphate synthetase 1/SEPHS1.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Rat
1. Gross, M. B. Personal Communication. Baltimore, Md. 2/28/2011. 2. Low, S. C., Harney, J. W., Berry, M. J. Cloning and functional characterization of human selenophosphate synthetase, an essential component of selenoprotein synthesis. J. Biol. Chem. 270: 21659-21664, 1995. 3. Tamura, T., Yamamoto, S., Takahata, M., Sakaguchi, H., Tanaka, H., Stadtman, T. C., Inagaki, K. Selenophosphate synthetase genes from lung adenocarcinoma cells: Sps1 for recycling L-selenocysteine and Sps2 for selenite assimilation. Proc. Nat. Acad. Sci. 101: 16162-16167, 2004.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SEPHS1

Target: SEPHS1 (Selenophosphate Synthetase 1 (SEPHS1))

Alternative Name: SEPHS1

Background:

Synonyms: Protein NDRG3,N-myc downstream-regulated gene 3 protein,NDRG3,

Tissue Specificity: Ubiquitous. Highly expressed in brain. .

Background: Selenide, water dikinase 1 is an enzyme that in humans is encoded by the SEPHS1 gene. This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons.

Molecular Weight: 50 kDa

Gene ID: 22929

UniProt: P49903