Annexin A2 antibody (N-Term)

Catalog No. ABIN7603195

The Rabbit Polyclonal anti-Annexin A2 antibody has been validated for WB and FACS. It is suitable to detect Annexin A2 in samples from Human, Mouse and Rat.

Quick Overview for Annexin A2 antibody (N-Term) (ABIN7603195)

Target: Annexin A2 (ANXA2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin A2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-Annexin A2 Antibody

Binding Specificity: N-Term

Purpose: Anti-Annexin A2/ANXA2 Antibody Picoband®

Characteristics: Anti-Annexin A2/ANXA2 Antibody Picoband® (ABIN7603195). Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ANXA2, which shares 92.9% and 100% amino acid (aa) sequence identity with mouse and rat ANXA2, respectively.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Huang, K.-S., Wallner, B. P., Mattaliano, R. J., Tizard, R., Burne, C., Frey, A., Hession, C., McGray, P., Sinclair, L. K., Chow, E. P., Browning, J. L., Ramachandran, K. L., Tang, J., Smart, J. E., Pepinsky, R. B. Two human 35 kd inhibitors of phospholipase A2 are related to substrates of pp60(v-src) and of the epidermal growth factor receptor/kinase. Cell 46: 191-199, 1986. 2. Huebner, K., Cannizzaro, L. A., Croce, C. M., Frey, A. Z., Wallner, B. P., Hecht, B. K., Hecht, F. Chromosome localization of the human genes for lipocortin I and the lipocortin II family. (Abstract) Cytogenet. Cell Genet. 46: 631 only, 1987. 3. Huebner, K., Cannizzaro, L. A., Frey, A. Z., Hecht, B. K., Hecht, F., Croce, C. M., Wallner, B. P. Chromosomal localization of the human genes for lipocortin I and lipocortin II. Oncogene Res. 2: 299-310, 1988.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for Annexin A2

Target: Annexin A2 (ANXA2)

Alternative Name: ANXA2

Background: Annexin A2 also known as annexin II is a protein that in humans is encoded by the ANXA2 gene. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms.

Molecular Weight: 39 kDa

Gene ID: 302

UniProt: P07355

Pathways: S100 Proteins