Annexin A2 antibody (N-Term)

Catalog No. ABIN391619

There are 2+ publications for this product available. The Rabbit Polyclonal anti-Annexin A2 antibody is suitable to detect Annexin A2 in samples from Human and Mouse. It has been validated for WB and IHC (p).

Quick Overview for Annexin A2 antibody (N-Term) (ABIN391619)

Target: Annexin A2 (ANXA2)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin A2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB15421

Product Details anti-Annexin A2 Antibody

Binding Specificity: AA 19-49, N-Term

Predicted Reactivity: B, Pig, Rat, Sh

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ANXA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-49 amino acids from the N-terminal region of human ANXA2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-Annexin A2 antibody (ABIN391619)

Li, Syrovets, Simmet, Ding, Xu, Chen, Zhu, Gao: "Plasmin induces intercellular adhesion molecule 1 expression in human endothelial cells via nuclear factor-?B/mitogen-activated protein kinases-dependent pathways." in: Experimental biology and medicine (Maywood, N.J.), Vol. 238, Issue 2, pp. 176-86, (2013) (PubMed).

Li, Ke, Zhang, Shen, Xu, Wang, Yu, Leng, Wang: "Plasmin plays an essential role in amplification of psoriasiform skin inflammation in mice." in: PLoS ONE, Vol. 6, Issue 2, pp. e16483, (2011) (PubMed).

Target Details for Annexin A2

Target: Annexin A2 (ANXA2)

Alternative Name: ANXA2

Background: ANXA2 is a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption.

Molecular Weight: 38604

Gene ID: 302

NCBI Accession: NP_001002857, NP_001002858, NP_001129487, NP_004030

UniProt: P07355

Pathways: S100 Proteins