GAS2 antibody (N-Term)

Catalog No. ABIN7603220

This anti-GAS2 antibody is a Rabbit Polyclonal antibody detecting GAS2 in WB and FACS. Suitable for Human, Mouse and Rat.

Quick Overview for GAS2 antibody (N-Term) (ABIN7603220)

Target: GAS2 (Growth Arrest-Specific 2 (GAS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAS2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-GAS2 Antibody

Binding Specificity: N-Term

Purpose: Anti-GAS2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-GAS2 Antibody Picoband® (ABIN7603220). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human GAS2, identical to the related mouse sequences.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Brancolini, C., Bottega, S., Schneider, C. Gas2, a growth arrest-specific protein, is a component of the microfilament network system. J. Cell Biol. 117: 1251-1261, 1992. 2. Collavin, L., Buzzai, M., Saccone, S., Bernard, L., Federico, C., DellaValle, G., Brancolini, C., Schneider, C. cDNA characterization and chromosome mapping of the human GAS2 gene. Genomics 48: 265-269, 1998. 3. Colombo, M. P., Martinotti, A., Howard, T. A., Schneider, C., D'Eustachio, P., Seldin, M. F. Localization of growth arrest-specific genes on mouse chromosomes 1, 7, 8, 11, 13, and 16. Mammalian Genome 2: 130-134, 1992.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for GAS2

Target: GAS2 (Growth Arrest-Specific 2 (GAS2))

Alternative Name: GAS2

Background:

Synonyms: Gap junction gamma-1 protein,Connexin-45,Cx45,Gap junction alpha-7 protein,GJC1,GJA7,

Tissue Specificity: Ubiquitously expressed.

Background: Growth arrest-specific protein 2 is a protein that in humans is encoded by the GAS2 gene. The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Alternative splicing results in multiple transcript variants.

Molecular Weight: 35 kDa

Gene ID: 2620

UniProt: O43903

Pathways: Caspase Cascade in Apoptosis