USP22 antibody (N-Term)

Catalog No. ABIN7603248

This Rabbit Polyclonal antibody specifically detects USP22 in WB. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for USP22 antibody (N-Term) (ABIN7603248)

Target: USP22 (Ubiquitin Specific Peptidase 22 (USP22))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP22 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-USP22 Antibody

Binding Specificity: N-Term

Purpose: Anti-USP22 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-USP22 Antibody Picoband® (ABIN7603248). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human USP22, which shares 89.5% amino acid (aa) sequence identity with mouse USP22.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
1. Cai, Z., Zhang, M.-X., Tang, Z., Zhang, Q., Ye, J., Xiong, T.-C., Zhang, Z.-D., Zhong, B. USP22 promotes IRF3 nuclear translocation and antiviral responses by deubiquitinating the importin protein KPNA2. J. Exp. Med. 217: e20191174, 2020. Note: Electronic Article. 2. Cortez, J. T., Montauti, E., Shifrut, E., Gatchalian, J., Zhang, Y., Shaked, O., Xu, Y., Roth, T. L., Simeonov, D. R., Zhang, Y., Chen, S., Li, Z., and 13 others. CRISPR screen in regulatory T cells reveals modulators of Foxp3. Nature 582: 416-420, 2020. 3. Gross, M. B. Personal Communication. Baltimore, Md. 9/3/2020.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for USP22

Target: USP22 (Ubiquitin Specific Peptidase 22 (USP22))

Alternative Name: USP22

Background:

Synonyms: Kallikrein-2, Glandular kallikrein-1, hGK-1, Tissue kallikrein-2, KLK2,

Background: Ubiquitin specific peptidase 22 is a protein that in humans is encoded by the USP22 gene on chromosome 17. Enables enzyme binding activity, nuclear receptor coactivator activity, and thiol-dependent deubiquitinase. Contributes to H4 histone acetyltransferase activity. Involved in positive regulation of mitotic cell cycle, positive regulation of transcription, DNA-templated, and protein modification by small protein conjugation or removal. Part of SAGA complex.

Molecular Weight: 68 kDa

Gene ID: 23326