YAP1 antibody (pSer127)

Catalog No. ABIN7603266

This Rabbit Monoclonal antibody specifically detects YAP1 in WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for YAP1 antibody (pSer127) (ABIN7603266)

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This YAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: GAB-25

Product Details anti-YAP1 Antibody

Binding Specificity: pSer127

Purpose: Anti-Phospho-YAP1 (S127) Rabbit Monoclonal Antibody

Characteristics: Anti-Phospho-YAP1 Rabbit Monoclonal Antibody (ABIN7603266). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human YAP1

Isotype: IgG

Application Details

Application Notes: WB 1:5000-1:20000
IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for YAP1

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Alternative Name: YAP1

Background:

Synonyms: Transcriptional coactivator YAP1,Yes-associated protein 1,Protein yorkie homolog,Yes-associated protein YAP65 homolog,YAP1,YAP65,

Tissue Specificity: Increased expression seen in some liver and prostate cancers. Isoforms lacking the transactivation domain found in striatal neurons of patients with Huntington disease (at protein level). .

Molecular Weight: 70, 75 kDa

UniProt: P46937

Pathways: MAPK Signaling, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha