PRKAA2 antibody (pSer491)

Catalog No. ABIN7603341

This Rabbit Monoclonal antibody specifically detects PRKAA2 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PRKAA2 antibody (pSer491) (ABIN7603341)

Target: PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PRKAA2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: HFI-16

Product Details anti-PRKAA2 Antibody

Binding Specificity: pSer491

Purpose: Anti-Phospho-AMPK alpha 2 (S491) PRKAA2 Rabbit Monoclonal Antibody

Characteristics: Anti-Phospho-AMPK alpha 2 PRKAA2 Rabbit Monoclonal Antibody (ABIN7603341). Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human AMPK alpha 2

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for PRKAA2

Target: PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))

Alternative Name: PRKAA2

Background:

Synonyms: 5'-AMP-activated protein kinase catalytic subunit alpha-2,AMPK subunit alpha-2,2.7.11.1 ,Acetyl-CoA carboxylase kinase,ACACA kinase,2.7.11.27 ,Hydroxymethylglutaryl-CoA reductase kinase,HMGCR kinase,2.7.11.31 ,PRKAA2,AMPK, AMPK2,

Tissue Specificity: Isoform TrkB is expressed in the central and peripheral nervous system. In the central nervous system (CNS), expression is observed in the cerebral cortex, hippocampus, thalamus, choroid plexus, granular layer of the cerebellum, brain stem, and spinal cord. In the peripheral nervous system, it is expressed in many cranial ganglia, the ophthalmic nerve, the vestibular system, multiple facial structures, the submaxillary glands, and dorsal root ganglia. Isoform TrkB-T1 is mainly expressed in the brain but also detected in other tissues including pancreas, kidney and heart. Isoform TrkB-T-Shc is predominantly expressed in the brain. .

Molecular Weight: 130 kDa

UniProt: P54646

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, Warburg Effect