CBL antibody (pSer669)

Catalog No. ABIN7603353

This Rabbit Monoclonal antibody specifically detects CBL in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CBL antibody (pSer669) (ABIN7603353)

Target: CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CBL antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 28C46

Product Details anti-CBL Antibody

Binding Specificity: pSer669

Purpose: Anti-Phospho-CBL (S669) Rabbit Monoclonal Antibody

Characteristics: Anti-Phospho-CBL Rabbit Monoclonal Antibody (ABIN7603353). Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Phospho-CBL (S669)

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for CBL

Target: CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))

Alternative Name: CBL

Background:

Synonyms: Focal adhesion kinase 1,FADK 1,2.7.10.2,Focal adhesion kinase-related nonkinase,FRNK,Protein phosphatase 1 regulatory subunit 71,PPP1R71,Protein-tyrosine kinase 2,p125FAK,pp125FAK,PTK2,FAK, FAK1,

Tissue Specificity: Detected in B and T-lymphocytes. Isoform 1 and isoform 6 are detected in lung fibroblasts (at protein level). Ubiquitous. .

Molecular Weight: 120 kDa

UniProt: P22681

Pathways: TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals