INPP5D antibody (pTyr1020)

Catalog No. ABIN7603424

The Rabbit Monoclonal anti-INPP5D antibody (Clone HFF-9) (ABIN7603424) specifically detects INPP5D in WB, IF, IP and ICC. The antibody is reactive with Human samples.

Quick Overview for INPP5D antibody (pTyr1020) (ABIN7603424)

Target: INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This INPP5D antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: HFF-9

Product Details anti-INPP5D Antibody

Binding Specificity: pTyr1020

Purpose: Anti-Phospho-SHIP (Y1020) INPP5D Rabbit Monoclonal Antibody

Characteristics: Anti-Phospho-SHIP INPP5D Rabbit Monoclonal Antibody (ABIN7603424). Tested in WB, ICC/IF, IP applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human SHIP

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
ICC/IF 1:50-200
IP 1:20

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for INPP5D

Target: INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))

Alternative Name: INPP5D

Background:

Synonyms: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1,3.1.3.86,Inositol polyphosphate-5-phosphatase of 145 kDa,SIP-145,SH2 domain-containing inositol 5'-phosphatase 1,SH2 domain-containing inositol phosphatase 1,SHIP-1,p150Ship,hp51CN,INPP5D,SHIP, SHIP1,

Tissue Specificity: Specifically expressed in immune and hematopoietic cells. Expressed in bone marrow and blood cells. Levels vary considerably within this compartment. Present in at least 74 % of immature CD34+ cells, whereas within the more mature population of CD33+ cells, it is present in only 10 % of cells. Present in the majority of T-cells, while it is present in a minority of B-cells (at protein level). .

Molecular Weight: 40 kDa

UniProt: Q92835

Pathways: TCR Signaling, BCR Signaling, Warburg Effect