Crk antibody (pTyr221)

Catalog No. ABIN7603445

The Rabbit Monoclonal anti-Crk antibody (Clone FDE-3) (ABIN7603445) specifically detects Crk in WB, IF and ICC. The antibody is reactive with Human samples.

Quick Overview for Crk antibody (pTyr221) (ABIN7603445)

Target: Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Crk antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: FDE-3

Product Details anti-Crk Antibody

Binding Specificity: pTyr221

Purpose: Anti-Phospho-CrkII (Tyr221) Rabbit Monoclonal Antibody

Characteristics: Anti-Phospho-CrkII (Tyr221) Rabbit Monoclonal Antibody (ABIN7603445). Tested in WB, ICC/IF applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Phospho-CrkII (Tyr221)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
ICC/IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for Crk

Target: Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

Alternative Name: CRK

Background:

Synonyms: Adapter molecule crk,Proto-oncogene c-Crk,p38,CRK,

Tissue Specificity: Expressed in brain, and to a lesser extent in lung, kidney and testis.

Molecular Weight: 85 kDa

UniProt: P46108

Pathways: Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor