AGO2 antibody

Catalog No. ABIN7604036

The Rabbit Monoclonal anti-AGO2 antibody (Clone AODE-1) (ABIN7604036) specifically detects AGO2 in WB, IHC, IF, FACS, ICC and IP. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for AGO2 antibody (ABIN7604036)

Target: AGO2 (Argonaute 2 (AGO2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This AGO2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: AODE-1

Product Details anti-AGO2 Antibody

Purpose: Anti-Argonaute 2 AGO2 Rabbit Monoclonal Antibody

Characteristics: Anti-Argonaute 2 AGO2 Rabbit Monoclonal Antibody (ABIN7604036). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Argonaute 2

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200
IP 1:20
FC 1:20

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for AGO2

Target: AGO2 (Argonaute 2 (AGO2))

Alternative Name: AGO2

Background:

Synonyms: Protein argonaute-2 ,Argonaute2 ,hAgo2,3.1.26.n2 ,Argonaute RISC catalytic component 2,Eukaryotic translation initiation factor 2C 2 ,eIF-2C 2 ,eIF2C 2 ,PAZ Piwi domain protein,PPD,Protein slicer ,AGO2,EIF2C2,

Tissue Specificity: Expressed on the apical surface of epithelial cells, especially of airway passages, breast and uterus. Also expressed in activated and unactivated T-cells. Overexpressed in epithelial tumors, such as breast or ovarian cancer and also in non-epithelial tumor cells. Isoform 7 is expressed in tumor cells only. .

Molecular Weight: 97 kDa

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization