CASP14 antibody
Quick Overview for CASP14 antibody (ABIN7604227)
Target
See all CASP14 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Caspase-14 Rabbit Monoclonal Antibody
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Characteristics
- Anti-Caspase-14 Rabbit Monoclonal Antibody (ABIN7604227). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human Caspase-14
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Isotype
- IgG
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Application Notes
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WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:50
FC 1:50 -
Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
- Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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Concentration
- Lot specific
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))
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Alternative Name
- CASP14
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Background
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Synonyms: Caspase-14,CASP-14,3.4.22.-,Caspase-14 subunit p17, mature form,Caspase-14 subunit p10, mature form,Caspase-14 subunit p20, intermediate form,Caspase-14 subunit p8, intermediate form,CASP14,
Tissue Specificity: Expressed in keratinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels (PubMed:11175259). The p17/10 mature form is expressed in epidermis stratum corneum, the p20/p8 intermediate form in epidermis upper granular cells of the stratum granulosum (PubMed:22825846). .
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Molecular Weight
- 36 kDa
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UniProt
- P31944
Target
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