CBS antibody

Catalog No. ABIN7604259

This Rabbit Monoclonal antibody specifically detects CBS in WB, IHC, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for CBS antibody (ABIN7604259)

Target: CBS (Cystathionine-beta-Synthase (CBS))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CBS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: 20C55

Product Details anti-CBS Antibody

Purpose: Anti-CBS Rabbit Monoclonal Antibody

Characteristics: Anti-CBS Rabbit Monoclonal Antibody (ABIN7604259). Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human CBS

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for CBS

Target: CBS (Cystathionine-beta-Synthase (CBS))

Alternative Name: CBS

Background:

Synonyms: E3 ubiquitin-protein ligase parkin,Parkin,6.3.2.-,Parkinson juvenile disease protein 2,Parkinson disease protein 2,PARK2,PRKN,

Tissue Specificity: Highly expressed in the brain including the substantia nigra. Expressed in heart, testis and skeletal muscle. Expression is down-regulated or absent in tumor biopsies, and absent in the brain of PARK2 patients. Overexpression protects dopamine neurons from kainate-mediated apoptosis. Found in serum (at protein level). .

Molecular Weight: 61 kDa

UniProt: P35520