CDC16 antibody

Catalog No. ABIN7604375

The Rabbit Monoclonal anti-CDC16 antibody (Clone IOI-3) (ABIN7604375) specifically detects CDC16 in WB, IF and ICC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CDC16 antibody (ABIN7604375)

Target: CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CDC16 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: IOI-3

Product Details anti-CDC16 Antibody

Purpose: Anti-Cdc16/APC6 Rabbit Monoclonal Antibody

Characteristics: Anti-Cdc16/APC6 Rabbit Monoclonal Antibody (ABIN7604375). Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Cdc16/APC6

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
ICC/IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for CDC16

Target: CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

Alternative Name: CDC16

Background:

Synonyms: Cell division cycle protein 16 homolog,Anaphase-promoting complex subunit 6,APC6,CDC16 homolog,CDC16Hs,Cyclosome subunit 6,CDC16,ANAPC6,

Tissue Specificity: According to PubMed:9858585, highest levels of expression in adult testis, thymus and brain. Lower levels in placenta, spleen and colon. Consistently elevated levels in tumor- derived cells compared to non-transformed proliferating cells. According to PubMed:9840927: low levels in thymus, prostate, brain, skeletal muscle, and kidney. Elevated levels in lung. According to PubMed:9840943 highly expressed in testis, placenta, thymus and brain. In a lesser extent in small intestine and colon.

Molecular Weight: 78 kDa

UniProt: Q13042

Pathways: Regulation of Actin Filament Polymerization