CRX antibody

Catalog No. ABIN7604512

The Rabbit Monoclonal anti-CRX antibody is suitable to detect CRX in samples from Human. It has been validated for WB and IHC.

Quick Overview for CRX antibody (ABIN7604512)

Target: CRX (Cone-Rod Homeobox (CRX))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CRX antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: AFIO-3

Product Details anti-CRX Antibody

Purpose: Anti-CRX Monoclonal Antibody

Characteristics: Anti-CRX Monoclonal Antibody (ABIN7604512). Tested in WB, IHC applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human CRX Binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, e.g. NRL and RX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IHC 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for CRX

Target: CRX (Cone-Rod Homeobox (CRX))

Alternative Name: CRX

Background:

Synonyms: Caspase-10,CASP-10,3.4.22.63,Apoptotic protease Mch-4,FAS-associated death domain protein interleukin-1B-converting enzyme 2,FLICE2,ICE-like apoptotic protease 4,Caspase-10 subunit p23/17,Caspase-10 subunit p12,CASP10,MCH4,

Tissue Specificity: Detectable in most tissues. Lowest expression is seen in brain, kidney, prostate, testis and colon.

Molecular Weight: 68 kDa

UniProt: O43186