DARC antibody

Catalog No. ABIN7604606

The Rabbit Monoclonal anti-DARC antibody (Clone 19A90) (ABIN7604606) specifically detects DARC in WB, IHC, IF, FACS, IP and ICC. The antibody is reactive with Human and Mouse samples.

Quick Overview for DARC antibody (ABIN7604606)

Target: DARC (Duffy Blood Group, Chemokine Receptor (DARC))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This DARC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: 19A90

Product Details anti-DARC Antibody

Purpose: Anti-DARC Rabbit Monoclonal Antibody

Characteristics: Anti-DARC Rabbit Monoclonal Antibody (ABIN7604606). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human DARC

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200
IP 1:50
FC 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for DARC

Target: DARC (Duffy Blood Group, Chemokine Receptor (DARC))

Alternative Name: ACKR1

Background:

Synonyms: G1/S-specific cyclin-E2,CCNE2,

Tissue Specificity: According to PubMed:9858585, highest levels of expression in adult testis, thymus and brain. Lower levels in placenta, spleen and colon. Consistently elevated levels in tumor- derived cells compared to non-transformed proliferating cells. According to PubMed:9840927: low levels in thymus, prostate, brain, skeletal muscle, and kidney. Elevated levels in lung. According to PubMed:9840943 highly expressed in testis, placenta, thymus and brain. In a lesser extent in small intestine and colon.

Molecular Weight: 35 kDa

UniProt: Q16570