CTNND1 antibody

Catalog No. ABIN7604632

The Rabbit Monoclonal anti-CTNND1 antibody has been validated for WB, IHC, IF, IP and ICC. It is suitable to detect CTNND1 in samples from Human, Mouse and Rat.

Quick Overview for CTNND1 antibody (ABIN7604632)

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CTNND1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: GI-3

Product Details anti-CTNND1 Antibody

Purpose: Anti-delta 1 Catenin/p120 Catenin Rabbit Monoclonal Antibody

Characteristics: Anti-delta 1 Catenin/p120 Catenin Rabbit Monoclonal Antibody (ABIN7604632). Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human delta 1 Catenin/p120 Catenin

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:50-1:100
ICC/IF 1:50-1:100
IP 1:30

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for CTNND1

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Alternative Name: CTNND1

Background:

Synonyms: Catenin delta-1,Cadherin-associated Src substrate,CAS,p120 catenin,p120 (ctn),p120 (cas),CTNND1,KIAA0384,

Tissue Specificity: Expressed in vascular endothelium. Melanocytes and melanoma cells primarily express the long isoform 1A, whereas keratinocytes express shorter isoforms, especially 3A. The shortest isoform 4A, is detected in normal keratinocytes and melanocytes, and generally lost from cells derived from squamous cell carcinomas or melanomas. The C-terminal alternatively spliced exon B is present in the p120ctn transcripts in the colon, intestine and prostate, but lost in several tumor tissues derived from these organs. .

Molecular Weight: 68 kDa

UniProt: O60716

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling