Complement Factor H antibody

Catalog No. ABIN7604809

The Rabbit Monoclonal anti-Complement Factor H antibody is suitable to detect Complement Factor H in samples from Human. It has been validated for WB, ICC and IF.

Quick Overview for Complement Factor H antibody (ABIN7604809)

Target: Complement Factor H (CFH)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Complement Factor H antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: ACCI-3

Product Details anti-Complement Factor H Antibody

Purpose: Anti-Factor H CFH Monoclonal Antibody

Characteristics: Anti-Factor H CFH Monoclonal Antibody (ABIN7604809). Tested in WB, ICC/IF applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Factor H Factor H functions as a cofactor in the inactivation of C3b by factor I and also increases the rate of dissociation of the C3bBb complex (C3 convertase) and the (C3b) NBB complex (C5 convertase) in the alternative complement pathway.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
ICC/IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for Complement Factor H

Target: Complement Factor H (CFH)

Alternative Name: CFH

Background:

Synonyms: Metalloproteinase inhibitor 1,Erythroid-potentiating activity,EPA,Fibroblast collagenase inhibitor,Collagenase inhibitor,Tissue inhibitor of metalloproteinases 1,TIMP-1,TIMP1,CLGI, TIMP,

Tissue Specificity: Detected in rheumatoid synovial fluid (at protein level). .

Molecular Weight: 180 kDa

UniProt: P08603

Pathways: Complement System, Cellular Response to Molecule of Bacterial Origin