ARNT antibody

Catalog No. ABIN7605094

The Rabbit Monoclonal anti-ARNT antibody has been validated for WB and IHC. It is suitable to detect ARNT in samples from Human.

Quick Overview for ARNT antibody (ABIN7605094)

Target: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ARNT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: EAD-1

Product Details anti-ARNT Antibody

Purpose: Anti-HIF-1 beta ARNT Rabbit Monoclonal Antibody

Characteristics: Anti-HIF-1 beta ARNT Rabbit Monoclonal Antibody (ABIN7605094). Tested in WB, IHC applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human HIF-1 beta

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for ARNT

Target: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Alternative Name: ARNT

Background:

Synonyms: Aryl hydrocarbon receptor nuclear translocator,ARNT protein,Class E basic helix-loop-helix protein 2,bHLHe2,Dioxin receptor, nuclear translocator,Hypoxia-inducible factor 1-beta,HIF-1-beta,HIF1-beta,ARNT,BHLHE2,

Tissue Specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable. .

Molecular Weight: 16 kDa

UniProt: P27540

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect