SETD8 antibody

Catalog No. ABIN7605385

The Rabbit Monoclonal anti-SETD8 antibody has been validated for WB and FACS. It is suitable to detect SETD8 in samples from Human, Mouse and Rat.

Quick Overview for SETD8 antibody (ABIN7605385)

Target: SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SETD8 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: ADHO-11

Product Details anti-SETD8 Antibody

Purpose: Anti-KMT5A / SETD8 / Pr-SET7 Monoclonal Antibody

Characteristics: Anti-KMT5A / SETD8 / Pr-SET7 Monoclonal Antibody (ABIN7605385). Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human KMT5A / SETD8 / Pr-SET7 Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1) . H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
FC 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for SETD8

Target: SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))

Alternative Name: KMT5A

Background:

Synonyms: Kinesin-like protein KIFC1,Kinesin-like protein 2,Kinesin-related protein HSET,KIFC1,HSET, KNSL2,

Tissue Specificity: Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung.

Molecular Weight: 72 kDa