VEGF antibody (AA 27-120)

Catalog No. ABIN727205

The Rabbit Polyclonal anti-VEGF antibody has been validated for WB, ELISA, IHC (p), IHC (fro), IF (p) and FACS. It is suitable to detect VEGF in samples from Human, Mouse, Rat, Pig and Goat. There are 14+ publications available.

Quick Overview for VEGF antibody (AA 27-120) (ABIN727205)

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Reactivity: Human, Mouse, Rat, Pig, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VEGF antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)

Product Details anti-VEGF Antibody

Binding Specificity: AA 27-120

Cross-Reactivity: Goat, Human, Mouse, Pig, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VEGF

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-VEGF antibody (ABIN727205)

Bi, Zhang, Du, Zhang, Deng, Liu, Zhang: "Peripheral serotonin regulates postoperative intra-abdominal adhesion formation in mice." in: Scientific reports, Vol. 7, Issue 1, pp. 10001, (2019) (PubMed).

Chen, Zhao, Li, Shou, Zheng, Li, Qi, Yu: "Circulating fibrocyte mobilization in negative pressure wound therapy." in: Journal of cellular and molecular medicine, Vol. 21, Issue 8, pp. 1513-1522, (2018) (PubMed).

Varghese, Joseph, S R, B S, Sreelekha: "The inhibitory effect of anti- tumor polysaccharide from Punica granatum on metastasis." in: International journal of biological macromolecules, Vol. 103, pp. 1000-1010, (2017) (PubMed).

Yasukawa, Fujihara, Fujimori, Kawaguchi, Yamada, Nakayama, Yamamoto, Kishi, Hamada, Masutani: "Synergetic Effects of PARP Inhibitor AZD2281 and Cisplatin in Oral Squamous Cell Carcinoma in Vitro and in Vivo." in: International journal of molecular sciences, Vol. 17, Issue 3, pp. 272, (2016) (PubMed).

Wang, Hao, Shi, Pu, Wang: "Effects of minocycline on apoptosis and angiogenesis-related protein expression in a rat model of intracerebral hemorrhage." in: Neural regeneration research, Vol. 7, Issue 8, pp. 595-600, (2015) (PubMed).

Li, Dong, Wei, Wang, Zhang, Li: "Fatty acid synthase mediates the epithelial-mesenchymal transition of breast cancer cells." in: International journal of biological sciences, Vol. 10, Issue 2, pp. 171-80, (2014) (PubMed).

Zhang, Li, Li, Chang, Chen, Jiang, Zhao, Guo: "Expression and localization of the vascular endothelial growth factor and changes of microvessel density during hair follicle development of Liaoning cashmere goats." in: Genetics and molecular research : GMR, Vol. 12, Issue 4, pp. 6424-32, (2014) (PubMed).

Zeng, Li, Dong, Ma, Jiang, Jin, Tu: "Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis." in: European journal of pharmacology, Vol. 714, Issue 1-3, pp. 261-73, (2013) (PubMed).

Ryzhov, Goldstein, Novitskiy, Blackburn, Biaggioni, Feoktistov: "Role of A2B adenosine receptors in regulation of paracrine functions of stem cell antigen 1-positive cardiac stromal cells." in: The Journal of pharmacology and experimental therapeutics, Vol. 341, Issue 3, pp. 764-74, (2012) (PubMed).

Qi, Qian, Sun, Liu, Wu, Sun: "Inhaled NO contributes to lung repair in piglets with acute respiratory distress syndrome via increasing circulating endothelial progenitor cells." in: PLoS ONE, Vol. 7, Issue 3, pp. e33859, (2012) (PubMed).

Guo, Chen, Huang, Li: "Combinatorial effects of naomai yihao capsules and vascular endothelial growth factor gene-transfected bone marrow mesenchymal stem cells on angiogenesis in cerebral ischemic tissues in rats." in: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, Vol. 32, Issue 1, pp. 87-92, (2012) (PubMed).

Target Details for VEGF

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Alternative Name: VEGF

Background:

Synonyms: VPF, VEGF, MVCD1, Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VEGFA

Background: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.

Gene ID: 7422

UniProt: P15692