PARP1 antibody

Catalog No. ABIN7605859

The Rabbit Monoclonal anti-PARP1 antibody has been validated for WB, IHC, IF and ICC. It is suitable to detect PARP1 in samples from Human, Mouse and Rat.

Quick Overview for PARP1 antibody (ABIN7605859)

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PARP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: ABCG-16

Product Details anti-PARP1 Antibody

Purpose: Anti-PARP PARP1 Rabbit Monoclonal Antibody

Characteristics: Anti-PARP PARP1 Rabbit Monoclonal Antibody (ABIN7605859). Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human PARP

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000
IHC 1:100-1:500
ICC/IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for PARP1

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Alternative Name: PARP1

Background:

Synonyms: Poly [ADP-ribose] polymerase 1,PARP-1,2.4.2.30,ADP-ribosyltransferase diphtheria toxin-like 1,ARTD1,NAD (+) ADP-ribosyltransferase 1,ADPRT 1,Poly[ADP-ribose] synthase 1,PARP1,ADPRT, PPOL,

Tissue Specificity: Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non- cancerous liver tissue. .

Molecular Weight: 70 kDa

UniProt: P09874

Pathways: Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location