ROCK2 antibody

Catalog No. ABIN7606201

The Rabbit Monoclonal anti-ROCK2 antibody has been validated for WB, IF and ICC. It is suitable to detect ROCK2 in samples from Human, Rat and Mouse.

Quick Overview for ROCK2 antibody (ABIN7606201)

Target: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ROCK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: ACDH-18

Product Details anti-ROCK2 Antibody

Purpose: Anti-ROCK2 Monoclonal Antibody

Characteristics: Anti-ROCK2 Monoclonal Antibody (ABIN7606201). Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human ROCK2 Regulates the assembly of the actin cytoskeleton. Promotes formation of stress fibers and of focal adhesion complexes. Plays a role in smooth muscle contraction.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000
ICC/IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for ROCK2

Target: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Alternative Name: ROCK2

Background:

Synonyms: Glutathione peroxidase 1,GPx-1,GSHPx-1,1.11.1.9,Cellular glutathione peroxidase,GPX1,

Tissue Specificity: Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients. .

Molecular Weight: 161 kDa

UniProt: O75116

Pathways: Microtubule Dynamics, WNT Signaling, Tube Formation