RRM2 antibody

Catalog No. ABIN7606215

This Rabbit Monoclonal antibody specifically detects RRM2 in WB, IF, IP and ICC. It exhibits reactivity toward Human.

Quick Overview for RRM2 antibody (ABIN7606215)

Target: RRM2 (Ribonucleotide Reductase M2 (RRM2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RRM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: AEAE-18

Product Details anti-RRM2 Antibody

Purpose: Anti-RRM2 Monoclonal Antibody

Characteristics: Anti-RRM2 Monoclonal Antibody (ABIN7606215). Tested in WB, ICC/IF, IP applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human RRM2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
ICC/IF 1:50-1:200
IP 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for RRM2

Target: RRM2 (Ribonucleotide Reductase M2 (RRM2))

Alternative Name: RRM2

Background:

Synonyms: Ubiquitin D,Diubiquitin,Ubiquitin-like protein FAT10,UBD,FAT10,

Tissue Specificity: Constitutively expressed in mature dendritic cells and B-cells. Mostly expressed in the reticuloendothelial system (e.g. thymus, spleen), the gastrointestinal system, kidney, lung and prostate gland. .

Molecular Weight: 45 kDa

UniProt: P31350

Pathways: Mitotic G1-G1/S Phases