CXCL12 antibody

Catalog No. ABIN7606253

This anti-CXCL12 antibody is a Rabbit Monoclonal antibody detecting CXCL12 in WB, ICC and IF. Suitable for Human.

Quick Overview for CXCL12 antibody (ABIN7606253)

Target: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CXCL12 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: IFO-3

Product Details anti-CXCL12 Antibody

Purpose: Anti-SDF1 CXCL12 Rabbit Monoclonal Antibody

Characteristics: Anti-SDF1 CXCL12 Rabbit Monoclonal Antibody (ABIN7606253). Tested in WB, ICC/IF applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human SDF1

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000
ICC/IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for CXCL12

Target: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Alternative Name: CXCL12

Background:

Synonyms: Stromal cell-derived factor 1,SDF-1,hSDF-1,C-X-C motif chemokine 12,Intercrine reduced in hepatomas,IRH,hIRH,Pre-B cell growth-stimulating factor,PBSF,SDF-1-beta (3-72),SDF-1-alpha (3-67),CXCL12,SDF1, SDF1A, SDF1B,

Tissue Specificity: Isoform Alpha and isoform Beta are ubiquitously expressed, with highest levels detected in liver, pancreas and spleen. Isoform Gamma is mainly expressed in heart, with weak expression detected in several other tissues. Isoform Delta, isoform Epsilon and isoform Theta have highest expression levels in pancreas, with lower levels detected in heart, kidney, liver and spleen. .

Molecular Weight: 82 kDa

UniProt: P48061

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling