PTTG1 antibody
Quick Overview for PTTG1 antibody (ABIN7606263)
Target
See all PTTG1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Securin Monoclonal Antibody
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Characteristics
- Anti-Securin Monoclonal Antibody (ABIN7606263). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.
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Purification
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human Securin Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.
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Isotype
- IgG
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Application Notes
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WB 1:1000-1:5000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:30
FC 1:50 -
Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
- Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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Concentration
- Lot specific
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))
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Alternative Name
- PTTG1
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Background
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Synonyms: Actin-related protein 2/3 complex subunit 5,Arp2/3 complex 16 kDa subunit,p16-ARC,ARPC5,ARC16,
Tissue Specificity: Predominantly in urogenital tissues.
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Molecular Weight
- 26 kDa
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UniProt
- O95997
Target
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