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PTTG1 antibody

This Rabbit Monoclonal antibody specifically detects PTTG1 in WB, IHC, IF, IP, ICC and FACS. It exhibits reactivity toward Human.
Catalog No. ABIN7606263

Quick Overview for PTTG1 antibody (ABIN7606263)

Target

See all PTTG1 Antibodies
PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))

Reactivity

  • 49
  • 12
  • 10
  • 1
Human

Host

  • 39
  • 11
  • 1
Rabbit

Clonality

  • 34
  • 17
Monoclonal

Conjugate

  • 33
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This PTTG1 antibody is un-conjugated

Application

  • 26
  • 21
  • 15
  • 8
  • 8
  • 7
  • 6
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone

ADFH-16
  • Purpose

    Anti-Securin Monoclonal Antibody

    Characteristics

    Anti-Securin Monoclonal Antibody (ABIN7606263). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.

    Purification

    Affinity-chromatography

    Immunogen

    A synthesized peptide derived from human Securin Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.

    Isotype

    IgG
  • Application Notes

    WB 1:1000-1:5000
    IHC 1:50-1:200
    ICC/IF 1:50-1:200
    IP 1:30
    FC 1:50

    Restrictions

    For Research Use only
  • Format

    Liquid

    Reconstitution

    Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

    Concentration

    Lot specific

    Buffer

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
  • Target

    PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))

    Alternative Name

    PTTG1

    Background

    Synonyms: Actin-related protein 2/3 complex subunit 5,Arp2/3 complex 16 kDa subunit,p16-ARC,ARPC5,ARC16,

    Tissue Specificity: Predominantly in urogenital tissues.

    Molecular Weight

    26 kDa

    UniProt

    O95997
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