Topoisomerase I antibody

Catalog No. ABIN7606547

This anti-Topoisomerase I antibody is a Rabbit Monoclonal antibody detecting Topoisomerase I in WB, IHC, IF, ICC and FACS. Suitable for Human, Mouse and Rat.

Quick Overview for Topoisomerase I antibody (ABIN7606547)

Target: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Topoisomerase I antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: FIG-20

Product Details anti-Topoisomerase I Antibody

Purpose: Anti-TOP1/Topoisomerase I Rabbit Monoclonal Antibody

Characteristics: Anti-TOP1/Topoisomerase I Rabbit Monoclonal Antibody (ABIN7606547). Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human TOP1

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200
FC 1:20

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for Topoisomerase I

Target: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Alternative Name: TOP1

Background:

Synonyms: DNA topoisomerase 1,5.99.1.2,DNA topoisomerase I,TOP1,

Tissue Specificity: Endothelial cells. .

Molecular Weight: 160-180 kDa

UniProt: P11387

Pathways: Caspase Cascade in Apoptosis, Stem Cell Maintenance