USP10 antibody

Catalog No. ABIN7606659

This Rabbit Monoclonal antibody specifically detects USP10 in WB, IF, IHC, IP and ICC. It exhibits reactivity toward Human.

Quick Overview for USP10 antibody (ABIN7606659)

Target: USP10 (Ubiquitin Specific Peptidase 10 (USP10))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This USP10 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: ADCB-21

Product Details anti-USP10 Antibody

Purpose: Anti-USP10 Monoclonal Antibody

Characteristics: Anti-USP10 Monoclonal Antibody (ABIN7606659). Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human USP10 Hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. Acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200
IP 1:20

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for USP10

Target: USP10 (Ubiquitin Specific Peptidase 10 (USP10))

Alternative Name: USP10

Background:

Synonyms: B-lymphocyte antigen CD20,B-lymphocyte surface antigen B1,Bp35,Leukocyte surface antigen Leu-16,Membrane-spanning 4-domains subfamily A member 1,CD20,MS4A1,CD20,

Tissue Specificity: Expressed on B-cells.

Molecular Weight: 25 kDa

UniProt: Q14694