USP28 antibody

Catalog No. ABIN7606666

The Rabbit Monoclonal anti-USP28 antibody has been validated for WB, IF, FACS and ICC. It is suitable to detect USP28 in samples from Human.

Quick Overview for USP28 antibody (ABIN7606666)

Target: USP28 (Ubiquitin Specific Peptidase 28 (USP28))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This USP28 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: ADDO-21

Product Details anti-USP28 Antibody

Purpose: Anti-USP28 Monoclonal Antibody

Characteristics: Anti-USP28 Monoclonal Antibody (ABIN7606666). Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human USP28 Deubiquitinase involved in DNA damage response checkpoint and MYC proto-oncogene stability. Involved in DNA damage induced apoptosis by specifically deubiquitinating proteins of the DNA damage pathway such as CLSPN.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
ICC/IF 1:50-1:200
FC 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for USP28

Target: USP28 (Ubiquitin Specific Peptidase 28 (USP28))

Alternative Name: USP28

Background:

Synonyms: Polypyrimidine tract-binding protein 2,Neural polypyrimidine tract-binding protein,Neurally-enriched homolog of PTB,PTB-like protein,PTBP2,NPTB, PTB, PTBLP,

Tissue Specificity: Mainly expressed in brain although also detected in other tissues like heart and skeletal muscle. Isoform 1 and isoform 2 are specifically expressed in neuronal tissues. Isoform 3 and isoform 4 are expressed in non-neuronal tissues. Isoform 5 and isoform 6 are truncated forms expressed in non- neuronal tissues. .

Molecular Weight: 100 kDa