Asialoglycoprotein Receptor 1 antibody (Biotin)

Catalog No. ABIN7608049

This Human Chimeric antibody specifically detects Asialoglycoprotein Receptor 1 in FACS. It exhibits reactivity toward Human.

Quick Overview for Asialoglycoprotein Receptor 1 antibody (Biotin) (ABIN7608049)

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Reactivity: Human

Host: Human, Rabbit

Clonality: Chimeric

Conjugate: This Asialoglycoprotein Receptor 1 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: DMC688

Product Details anti-Asialoglycoprotein Receptor 1 Antibody (Biotin)

Purpose: Biotinylated Anti-ASGR1 antibody(DMC688), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for Asialoglycoprotein Receptor 1

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Alternative Name: ASGR1

Background: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

UniProt: P07306, Q6FGQ5

Pathways: Thyroid Hormone Synthesis