CD44 antibody (Biotin)

Catalog No. ABIN7608117

This anti-CD44 antibody is a Human Chimeric antibody detecting CD44 in FACS. Suitable for Human.

Quick Overview for CD44 antibody (Biotin) (ABIN7608117)

Target: CD44

Reactivity: Human

Host: Human, Rabbit

Clonality: Chimeric

Conjugate: This CD44 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: DMC269

Product Details anti-CD44 Antibody (Biotin)

Purpose: Biotinylated Anti-CD44 antibody(DMC269), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for CD44

Target: CD44

Alternative Name: CD44

Background: The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling