CXCR3 antibody (Biotin)

Catalog No. ABIN7608178

This Rabbit Monoclonal antibody specifically detects CXCR3 in FACS and ELISA. It exhibits reactivity toward Human.

Quick Overview for CXCR3 antibody (Biotin) (ABIN7608178)

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CXCR3 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), ELISA

Clone: DM208

Product Details anti-CXCR3 Antibody (Biotin)

Purpose: Biotinylated Anti-CXCR3 antibody(DM208), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Application Details

Application Notes: ELISA 1:5000-10000, Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for CXCR3

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Alternative Name: CXCR3

Background: This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9:Mig (monokine induced by interferon-g), CXCL10:IP10 (interferon-g-inducible 10 kDa protein) and CXCL11:I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4:PF4 (PMID:12782716). [provided by RefSeq, Jun 2011]

UniProt: P49682