Interferon gamma antibody (Biotin)
Quick Overview for Interferon gamma antibody (Biotin) (ABIN7608269)
Target
See all Interferon gamma (IFNG) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Purpose
- Biotinylated Anti-IFNG antibody(1A2), IgG1 Chimeric mAb
-
Purification
- Purified from cell culture supernatant by affinity chromatography
-
Isotype
- IgG1
-
-
-
-
Application Notes
- ELISA 1/5000-10000
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 9 % trehalose is added as protectants before lyophilization.
-
Storage
- -20 °C,-80 °C
-
Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -81°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
-
Expiry Date
- 12 months
-
-
- Interferon gamma (IFNG)
-
Alternative Name
- IFNG
-
Background
- IFNγ is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease. Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens, mitogens, or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. IFNγ synthesis is induced by IL-2, FGF-basic, and EGF.
-
UniProt
- P01579
-
Pathways
- Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
Target
-