PVRL4 antibody (Biotin)

Catalog No. ABIN7608322

This Human Chimeric antibody specifically detects PVRL4 in FACS. It exhibits reactivity toward Human.

Quick Overview for PVRL4 antibody (Biotin) (ABIN7608322)

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Reactivity: Human

Host: Human, Rabbit

Clonality: Chimeric

Conjugate: This PVRL4 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: DMC438

Product Details anti-PVRL4 Antibody (Biotin)

Purpose: Biotinylated Anti-Nectin4 antibody(DMC438), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for PVRL4

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Alternative Name: NECTIN4

Background: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17:TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

UniProt: Q96NY8

Pathways: Cell-Cell Junction Organization