Adenylate Kinase 1 antibody (AA 131-194)

Catalog No. ABIN727593

This anti-Adenylate Kinase 1 antibody is a Rabbit Polyclonal antibody detecting Adenylate Kinase 1 in ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). Suitable for Human.

Quick Overview for Adenylate Kinase 1 antibody (AA 131-194) (ABIN727593)

Target: Adenylate Kinase 1 (AK1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adenylate Kinase 1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Adenylate Kinase 1 Antibody

Binding Specificity: AA 131-194

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Goat,Monkey

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Adenylate Kinase 1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Adenylate Kinase 1

Target: Adenylate Kinase 1 (AK1)

Alternative Name: Adenylate Kinase 1

Background:

Synonyms: Adenylate kinase isoenzyme 1, Adenylate kinase soluble, AK 1, AK1, AK-1, ATP AMP transphosphorylase, Myokinase, KAD1_HUMAN, ATP-AMP transphosphorylase 1.

Background: Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. [provided by RefSeq, Jul 2008].

Gene ID: 203

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process