Claudin 1 antibody (Cy7)

Catalog No. ABIN728209

This Rabbit Polyclonal antibody specifically detects Claudin 1 in WB and IF (p). It exhibits reactivity toward Human, Rat, Mouse, Dog and Pig.

Quick Overview for Claudin 1 antibody (Cy7) (ABIN728209)

Target: Claudin 1 (CLDN1)

Reactivity: Human, Rat, Mouse, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 1 antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Claudin 1 Antibody (Cy7)

Cross-Reactivity: Dog, Human, Mouse, Pig, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Claudin 1

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Claudin 1

Target: Claudin 1 (CLDN1)

Alternative Name: Claudin 1

Background:

Synonyms: claudin, Claudin1, CLD 1, CLD1, CLDN 1, CLDN1, ILVASC, SEMP 1, SEMP1, Senescence associated epithelial membrane protein 1, Senescence associated epithelial membrane protein.

Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq].

Molecular Weight: 23kDa

Gene ID: 9076

Pathways: Cell-Cell Junction Organization, Hepatitis C