TNNC1 antibody (AA 131-210)

Catalog No. ABIN728308

This Rabbit Polyclonal antibody specifically detects TNNC1 in WB, ELISA, IF (p), IHC (p), IF (cc) and IHC (fro). It exhibits reactivity toward Human, Mouse, Rat and Rabbit and has been mentioned in 7+ publications.

Quick Overview for TNNC1 antibody (AA 131-210) (ABIN728308)

Target: TNNC1 (Cardiac Troponin C (TNNC1))

Reactivity: Human, Mouse, Rat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNNC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TNNC1 Antibody

Binding Specificity: AA 131-210

Cross-Reactivity: Human, Mouse, Rabbit, Rat

Predicted Reactivity: Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Cardiac Troponin I

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TNNC1 antibody (ABIN728308)

Ruan, Zhu, Yin, Chen: "Inhibitor of p53-p21 pathway induces the differentiation of human umbilical cord derived mesenchymal stem cells into cardiomyogenic cells." in: Cytotechnology, Vol. 68, Issue 4, pp. 1257-65, (2016) (PubMed).

Ruan, Zhu, Yin, Chen: "Overexpressing NKx2.5 increases the differentiation of human umbilical cord drived mesenchymal stem cells into cardiomyocyte-like cells." in: Biomedicine & pharmacotherapy, Vol. 78, pp. 110-5, (2016) (PubMed).

Sharma, Han, Jang: "Rapid electrical immunoassay of the cardiac biomarker troponin I through dielectrophoretic concentration using imbedded electrodes." in: Biosensors & bioelectronics, Vol. 82, pp. 78-84, (2016) (PubMed).

Zhu, Ruan, Yin, Chen: "Expression and significance of DLL4--Notch signaling pathway in the differentiation of human umbilical cord derived mesenchymal stem cells into cardiomyocytes induced by 5-azacytidine." in: Cell biochemistry and biophysics, Vol. 71, Issue 1, pp. 249-53, (2015) (PubMed).

Liu, Li, Sun, Li, Du, Sun, Cao, Li, Jia, Wang, Chang, Yu, Wang, Peng: "The use of antibody modified liposomes loaded with AMO-1 to deliver oligonucleotides to ischemic myocardium for arrhythmia therapy." in: Biomaterials, Vol. 35, Issue 11, pp. 3697-707, (2014) (PubMed).

Zhao, Yang, Zhao: "Rho-associated protein kinases play an important role in the differentiation of rat adipose-derived stromal cells into cardiomyocytes in vitro." in: PLoS ONE, Vol. 9, Issue 12, pp. e115191, (2014) (PubMed).

Gao, Zhang, Ding, Chen, Hu, Jiang, Li, Chen, Wang, Ye, Zhu: "Common expression of stemness molecular markers and early cardiac transcription factors in human Wharton's jelly-derived mesenchymal stem cells and embryonic stem cells." in: Cell transplantation, Vol. 22, Issue 10, pp. 1883-900, (2014) (PubMed).

Target Details for TNNC1

Target: TNNC1 (Cardiac Troponin C (TNNC1))

Alternative Name: cardiac Troponin I

Background:

Synonyms: CMH7, RCM1, cTnI, CMD2A, TNNC1, CMD1FF, Troponin I, cardiac muscle, Cardiac troponin I, TNNI3

Background: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Gene ID: 7137

UniProt: P19429