Angiopoietin 1 antibody (AA 276-375) (Cy5.5)

Catalog No. ABIN728328

This anti-Angiopoietin 1 antibody is a Rabbit Polyclonal antibody detecting Angiopoietin 1 in WB, IF (cc) and IF (p). Suitable for Human, Mouse and Rat.

Quick Overview for Angiopoietin 1 antibody (AA 276-375) (Cy5.5) (ABIN728328)

Target: Angiopoietin 1 (ANGPT1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiopoietin 1 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Angiopoietin 1 Antibody (Cy5.5)

Binding Specificity: AA 276-375

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Angiopoietin 1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Angiopoietin 1

Target: Angiopoietin 1 (ANGPT1)

Alternative Name: Angiopoietin 1

Background:

Synonyms: AGP 1, AGP1, AGPT, ANG 1, ANG1, Angiopoietin1, Angiogenin, ANGPT 1, ANGPT1, ANGPT-1, Angiopoietin-1, Angiopoietin 1, ANG-1, angiopoietin-1 isoform 1 precursor, ANGP1_HUMAN.

Background: Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010].

Gene ID: 11600

Pathways: RTK Signaling, Glycosaminoglycan Metabolic Process