PKN2 antibody (AA 881-984)

Catalog No. ABIN729283

This Rabbit Polyclonal antibody specifically detects PKN2 in IHC (p), IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for PKN2 antibody (AA 881-984) (ABIN729283)

Target: PKN2 (Protein Kinase N2 (PKN2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKN2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PKN2 Antibody

Binding Specificity: AA 881-984

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PKN2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PKN2

Target: PKN2 (Protein Kinase N2 (PKN2))

Alternative Name: PKN2

Background:

Synonyms: protein kinase N2, Serine/threonine-protein kinase N2, Protein kinase C-like 2, Protease-activated kinase 2, PAK-2, Cardiolipin activated protein kinase Pak2, MGC150606, MGC71074, PAK2, PRK2, PRKCL2, PRO2042, Protein kinase C like 2, Protein kinase C related kinase 2.

Background: Protein-kinase-C-related kinases (PRKs) are part of the lipid-regulated protein kinases (PKC) which also include liver PAK & PKN. Human PRK1 and PRK2 share structurally similar catalytic domains, but less similar N-terminal regulatory regions suggesting different regulatory domain functions. PRK1 and PRK2, as well as a third member of this family, PRK3, show distinct patterns of expression in adult tissues. Additionally, the serine-threonine kinase PRK2 can be specifically cleaved by caspase-3 (and/or caspase-3-like subfamily members) during apoptosis

Gene ID: 5586

Pathways: Cell-Cell Junction Organization